By the numbers · 5 min read

Kidney donation by the numbers.

The real statistics behind why John needs you. And why one healthy person stepping forward can save lives well beyond the patient they came to help.

The waiting list, today

90,000+
People in the United States currently on the kidney transplant waiting list.
~3,000
People die every year in the U.S. while waiting for a kidney that never comes.
3 to 5 years
Average wait time for a deceased-donor kidney in most U.S. regions.
1 in 7
American adults have some form of chronic kidney disease, though most don't know it.

The waiting list is the bluntest statistic in kidney medicine. There are more people who need kidneys than there are kidneys available. Every year that gap gets wider. People die in line.

Living donation is the only path that gets shorter, not longer.

Why living donation matters

~6,500
Living kidney donations performed in the U.S. each year.
15-20 years
Average lifespan of a kidney from a living donor — roughly double the lifespan of a deceased-donor kidney.
98%
One-year success rate for living donor kidney transplants in the U.S.
90%
Five-year success rate for living donor kidney transplants.

A kidney from a living donor isn't just available faster. It works better, lasts longer, and gives the recipient a much higher quality of life than a deceased-donor kidney. The reason is simple: a living donor's kidney has never been without blood flow, never sat in cold storage, never been transported for hours. It goes directly from one healthy body to another.

The donor's side of the equation

3-5%
Rate of surgical complications for living kidney donors, most of them minor.
3 in 10,000
Historical mortality rate for living kidney donation surgery in the U.S.
2 to 4 weeks
Typical return to desk work after donor surgery.
70-80%
Of original kidney function remains after donation — plenty for normal life.

Living donors typically have life expectancy and overall health outcomes comparable to people who never donated. The remaining kidney grows slightly larger and takes on most of the work of two. Some Olympic athletes have donated kidneys and gone on to win medals afterward.

The risk isn't zero. No surgery's risk is zero. But it's small, it's well-understood, and you'll have full disclosure before you decide.

What paired donation chains have accomplished

50+
U.S. transplant centers partnered with the Alliance for Paired Kidney Donation (APKD).
9
People saved by APKD's longest single chain in the past year.
~3 months
Average wait time for APKD to find a chain match for an incompatible donor-recipient pair.
~1/3
Of willing kidney donors are incompatible with their intended recipient. Paired donation exists for exactly these people.

Paired donation isn't theoretical. APKD and similar national programs have been running for nearly two decades. They've completed thousands of transplants that would not have happened otherwise. The Nobel Prize in Economics in 2012 was awarded in part for the matching algorithm that makes these chains possible.

The Ascension St. John partnership that John is enrolled in is brand new in Oklahoma. But the underlying program is well-proven.

What this means for John

Here's the part that should sink in. The reason John is asking strangers to be tested isn't because he's run out of friends or family who care. He's asking strangers because the program works through strangers. The whole point of paired donation is that the network of donors and recipients is national, not personal.

The statistics above mean a few specific things for John's situation:

Be a number that matters.

The most powerful number in kidney medicine isn't 90,000. It's 1. One person stepping forward.

Call Ascension St. John: 918-744-2925

Sources

  • United Network for Organ Sharing (UNOS) waiting list statistics, optn.transplant.hrsa.gov, 2025-2026.
  • Organ Procurement and Transplantation Network (OPTN) annual data report, 2024-2025.
  • Alliance for Paired Kidney Donation public program data, paireddonation.org.
  • National Kidney Foundation, kidney.org, statistics and patient resources, 2025-2026.
  • Centers for Disease Control and Prevention, "Chronic Kidney Disease in the United States," 2023.
  • Roth, A.E., Sönmez, T., & Ünver, M.U., "Kidney Exchange," Quarterly Journal of Economics, 2004.

Numbers are approximate ranges drawn from publicly reported program data and may vary year to year. Verify specific figures with Ascension St. John Transplant Center or the National Kidney Foundation for current data.

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